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USNoticeOfficial ✓July 14, 2026· Federal Register

Psychedelic Drugs: Considerations for Clinical Investigations; Guidance for Industry; Availability

What happened

The Food and Drug Administration (FDA) announced the availability of a final guidance document titled "Psychedelic Drugs: Considerations for Clinical Investigations." This guidance, signed by Donald Trump, provides recommendations for companies designing clinical trials to evaluate psychedelic drugs for psychiatric and substance use disorders. This final guidance completes the draft guidance issued on June 26, 2023.

Why it matters

This guidance will shape how new psychedelic-based treatments are tested and potentially brought to market, influencing the future availability of these drugs for patients. It aims to address the unique challenges of studying psychedelic drugs in clinical trials.

Who it affects

  • Companies developing psychedelic drugs
  • Patients with psychiatric or substance use disorders
  • Clinical investigators of psychedelic drugs
  • Food and Drug Administration (FDA)
Receipts

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Read on Federal Register

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