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USRuleOfficial ✓October 2, 2026· Federal Register

Global Benchmark for Efficient Drug Pricing (GLOBE) Model

What happened

This final rule, signed by Donald Trump, implements the Global Benchmark for Efficient Drug Pricing Model (GLOBE Model). It is a mandatory Medicare payment model that will test an alternative method for calculating Medicare Part B drug inflation rebate amounts. This applies to certain separately payable Medicare Part B drugs and biological products under Original Medicare.

Why it matters

The model aims to reduce costs for beneficiaries receiving Original Medicare and for the Medicare program itself. It seeks to achieve these savings while ensuring the quality of care is maintained.

Who it affects

  • ›Original Medicare beneficiaries
  • ›The Medicare program
  • ›Manufacturers of certain Medicare Part B drugs
  • ›Manufacturers of certain Medicare Part B biological products
Receipts

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